Effects of Dalmazin on Luteal Cysts in Crossbreed Cows in Multan, Punjab (Pakistan)

This study was conducted on the crossbreed cows (Sahiwal x Friesian) n=323 maintained at the Multan Dairy Farm Vehari Road Multan. The study aims to assess the response of treatment of crossbreed cows identified to possess luteal cyst using the prostaglandin analogue. The animals which did not show estrus up to 80-100 days, post partum were considered as cystic disorder. These animals were initially examined through rectal palpation. Sixty five (20.12%) animal showed no visible estrus signs. The incidence of postpartum disorders were luteal cyst, 15 (4.64%), follicular cyst, 11 (3.40%), corpus luteum 12 (3.71%), persistent corpus luteum 12 (3.71%), Anoestrous 13 (4.02%), and cystic ovary 2 (0.61%) through rectal palpation in the crossbreed cows. Three clinical examinations with a 7 day interval were performed in these cows and blood samples were also collected for progesterone analysis through radioimmunoassay (RIA). The results of the rectal palpation were confirmed by plasma progesterone concentration. The concentration of the progesterone before treatment in the blood was 1.44±0.44 ng/ml, 1.12±0.56 ng/ml and 0.56±0.23 ng/ml during 1 st , 2nd and 3 rd week respectively. The 8 cows were found as heaving luteal cyst. The treatment with Dalmazin (PGF2α) changed the plasma concentration of progesterone and it was 1.25±0.47 ng/ml, 3.88±0.88 ng/ml and 6.03±1.91 ng/ml during 1 st , 2 nd and 3 rd week respectively. All the treated animals were responded, 75%were pregnant and 25% were in regular cycling. The dalmazin (PGF2α) treatment enhanced the reproductive efficiency of the crossbreed cows, which were suffering from luteal cyst.